Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag. #DynaTag can reveal nuanced TF occupancy behaviour and shed light on transcriptional regulation in health and disease. In small cell lung cancer #SCLC PDX models, it uncovered surprising gain-of-function p53, FOXA1 & MYC activity post-chemotherapy – not for ASCL1, NEUROD1, POU2F3 or YAP1. --> www.nature.com/articles/s41467-025-61797-9
