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Publications

The fruit derived from labor is the sweetest of pleasures

Publications

Selected Publications

  • R. Hänsel-Hertsch, A. Simeone, A. Shea, W.W.I. Hui, K.G. Zyner, G. Marsico, O.M. Rueda, A. Bruna, A. Martin, X. Zhang, S. Adhikari, D. Tannahill, C. Caldas, S. Balasubramanian
    Landscape of G-quadruplex DNA structural regions in breast cancer
    Nature Genetics (2020), 52: 878–883
  • R. Hänsel-Hertsch, J. Spiegel, G. Marsico, D. Tannahill, S. Balasubramanian
    Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing
    Nature Protocols (2018), 13: 551-564
  • R. Hänsel-Hertsch, M. Di Antonio, S. Balasubramanian
    DNA G‑quadruplexes in the human genome: detection, functions and therapeutic potential
    Nature Reviews Molecular Cell Biology (2017), 18: 279-284
  • R. Hänsel-Hertsch, D. Beraldi, S.V. Lensing, G. Marsico, K. Zyner, A. Parry, M. Di Antonio, J. Pike, H. Kimura, M. Narita, D. Tannahill, S. Balasubramanian
    G-quadruplex structures mark human regulatory chromatin
    Nature Genetics (2016), 10: 1267-72
  • S.V. Lensing, G. Marsico, R. Hänsel-Hertsch, E.Y. Lam, D. Tannahill, S. Balasubramanian
    DSBCapture: in situ capture and sequencing of DNA breaks
    Nature Methods (2016), 10: 855-7

2020

  • R. Hänsel-Hertsch, A. Simeone, A. Shea, W.W.I. Hui, K.G. Zyner, G. Marsico, O.M. Rueda, A. Bruna, A. Martin, X. Zhang, S. Adhikari, D. Tannahill, C. Caldas, S. Balasubramanian
    Landscape of G-quadruplex DNA structural regions in breast cancer
    Nature Genetics (2020), 52: 878–883

2019

  • M. Krafcikova, S. Dzatko, C. Caron, A. Granzhan, R. Fiala, T. Loja, MP. Teulade-Fichou, T. Fessl, R. Hänsel- Hertsch, JL Mergny, S. Foldynova-Trantirkova, L. Trantirek
    Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy
    Journal of the American Chemical Society (2019), 34: 13281-13285
  • M. Krafcikova, R. Hänsel-Hertsch, L. Trantirek, S. Foldynova-Trantirkova
    In Cell NMR Spectroscopy: Investigation of G-Quadruplex Structures Inside Living Xenopus laevis Oocytes
    Methods in Molecular Biology (2019), doi: 10.1007/ 978-1-4939-9666-7_25

2018

  • A. Parry, M. Hoare, D. Bihary, R. Hänsel-Hertsch, S. Smith, K. Tomimatsu, S. Balasubramanian, H. Kimura, S. Samarajiwa, M. Narita
    NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence
    Nature Communications (2018), 9: 1840
  • S. Mao, A. T. Ghanbarian, J. Spiegel, S. Martínez Cuesta, D. Beraldi, M. Di Antonio, G. Marsico, R. Hänsel- Hertsch, D. Tannahill, S. Balasubramanian
    DNA G-quadruplex structures mould the DNA methylome
    Nature Structure & Molecular Biology (2018)
  • R. Hänsel-Hertsch, J. Spiegel, G. Marsico, D. Tannahill, S. Balasubramanian
    Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing
    Nature Protocols (2018), 13: 551-564

2017

  • S. Dzatko, M. Krafcikova, R. Hänsel-Hertsch, T. Fessl, R. Fiala, T. Loja, D. Krafcik, JL Mergny, S. Foldynova- Trantirkova, L. Trantirek
    Evaluation of stability of DNA i-motifs in the nuclei of living mammalian cells
    Angewandte Chemie International Edition (2017), doi: 10.1002/anie.201712284
  • R. Hänsel-Hertsch, M. Di Antonio, S. Balasubramanian
    DNA G‑quadruplexes in the human genome: detection, functions and therapeutic potential
    Nature Reviews Molecular Cell Biology (2017), 18: 279-284

2016

  • S.V. Lensing, G. Marsico, R. Hänsel-Hertsch, E.Y. Lam, D. Tannahill, S. Balasubramanian
    DSBCapture: in situ capture and sequencing of DNA breaks
    Nature Methods (2016), 10: 855-7
  • R. Hänsel-Hertsch, D. Beraldi, S.V. Lensing, G. Marsico, K. Zyner, A. Parry, M. Di Antonio, J. Pike, H. Kimura, M. Narita, D. Tannahill, S. Balasubramanian
    G-quadruplex structures mark human regulatory chromatin
    Nature Genetics (2016), 10: 1267-72

2015

  • A.P. Jagtap, I. Krstic, N.C. Kunjir, R. Hänsel, T.F. Prisner, S.T. Sigurdsson
    Sterically shielded spin labels for in-cell EPR spectroscopy: Analysis of stability in reducing environment
    Free Radical Research (2015), 49: 78-85

2014

  • R. Hänsel, L.M. Luh, F. Löhr, I. Corbeski, L. Trantirek, V. Dötsch
    In-cell NMR and EPR spectroscopy of biomacromolecules
    Angewandte Chemie International Edition (2014), 53: 10300-14

2013

  • L.M. Luh, R. Hänsel, F. Löhr, D.K. Kirchner, K. Krauskopf, S. Pitzius, B. Schäfer, P. Tufar, I. Corbeski, P. Güntert, V. Dötsch
    Molecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition
    Journal of the American Chemical Society (2013), 135: 13796-803
  • R. Hänsel, F. Löhr, L. Trantirek, V. Dötsch
    High-resolution insight into G-overhang architecture
    Journal of the American Chemical Society (2013), 135: 2816-24

2012

  • R. Hänsel, S. Foldynova-Trantirkova, V. Dötsch, L. Trantirek
    Investigation of quadruplex structure under physiological conditions using In-cell NMR
    Topics in Current Chemistry (2012), 330: 47-65

2011

  • I. Krstić*, R. Hänsel*, O. Romainczyk, J.W. Engels, V. Dötsch, T.F. Prisner
    Long Range Distance Measurements on Nucleic Acids in cells by Pulsed EPR Spectroscopy
    Angewandte Chemie International Edition (2011), 50: 5070-4,
  • R. Hänsel, F. Löhr, S. Foldynova-Trantirkova, E. Bamberg, L. Trantirek, V. Dötsch
    The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions
    Nucleic Acids Research (2011), 39: 5768-75

2009

  • R. Hänsel, S. Foldynova-Trantirkova, F. Löhr, J. Buck, E. Bamberg, H. Schwalbe, V. Dötsch, L. Trantirek
    Evaluation of parameters critical for observing nucleic acids inside living Xenopus laevis oocytes by in-cell NMR spectroscopy
    Journal of the American Chemical Society (2009), 131: 15761-8

2007

  • S. Reckel, R. Hänsel, F. Löhr, V. Dötsch
    In-cell NMR spectroscopy
    Progress in Nuclear Magnetic Resonance Spectroscopy (2007), 51: 91-101
  • F. Löhr, R. Hänsel, V. Rogov, V. Dötsch
    Improved pulse sequences for sequence specific assignment of aromatic proton resonances in proteins
    Journal of Biomolecular NMR (2007), 37: 205-24

2006

  • Z. Serber, P. Selenko, R. Hänsel, S. Reckel, F. Löhr, J.E. Ferrell, G. Wagner, V. Dötsch
    Investigating macromolecules inside cultured and injected cells by in-cell NMR spectroscopy
    Nature Protocols (2006), 1: 2701-9